Fig. 4.

Novel dif modules carrying diverse accessory genes. (a) Presence and absence of dif modules identified in GR13 plasmids. Plasmids are ordered as in the rep gene phylogeny shown in Fig. 2, and membership of lineages 1, 2 and 3 is indicated. The presence of variant BREX and ADH segments are indicated by different shades of colour (b) Scaled diagrams of selected dif modules. (c) Scaled diagrams of accessory gene segments. Sequences in parts (b) and (c) were drawn to scale from GenBank accessions CP072528, CP073061, CU459140, AP024799, CP022299 and CP068175.