Table 4.
Trends in disease activity indices, CRP and faecal calprotectin over 12 months from baseline.
Variable, n. | Baseline [BL] | 3 months | 6 months | 12 months | p-value BL vs 12 months |
---|---|---|---|---|---|
HBI, median [IQR] | 1.0 [2.0], n = 110 | 0.0 [2.0], n = 89 | 0.0 [1.0], n = 82 | 0.0 [1.0], n = 78 | 0.104 |
SCCAI, median [IQR] | 1.0 [3.0], n = 57 | 1.0 [3.0], n = 55 | 0.0 [2.8], n = 40 | 0.0 [4.0], n = 41 | 0.003 |
CRP mg/L, median [IQR] | 4.0 [2.0], n = 178 | 2.0 [1.0], n = 159 | 1.0 [3.0], n = 141 | 2.0 [1.0], n = 132 | 0.008 |
FC, median µg/g [IQR] | 67.5 [143.5], n = 102 | 56.0 [161.5], n = 126 | 67.5 [135.0], n = 118 | 79.0 [138.50, n = 117 | 0.207 |
Steroid use [%] | 2 [1.1%] | 1 [0.6%] | 0 [0.0%] | 0 [0.0%] |
BL, baseline; n, number; CRP, C-reactive protein; HBI, Harvey-Bradshaw Index; IQR, interquartile range; SCCAI, Simple Clinical Colitis Activity Index; FC, faecal calprotectin.