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. 2022 Apr 7;16(9):1436–1446. doi: 10.1093/ecco-jcc/jjac053

Table 5.

Treatment persistence rates and biochemical parameters among patients switched to weekly or bi-weekly SC CT-P13 in patients on escalated intravenous infliximab dosing frequency prior to switch.

Every other week [n = 27] Weekly [n = 23] p-value
Treatment persistence rates
3 months 100% 96.3% 0.353
6 months 92.6% 95.7% 0.357
12 months 92.6% 95.7% 0.650
C-reactive protein [mg/L]
Baseline 3.0 [4.0] 1.0 [2.0] 0.014
3 months 2.0 [4.0] 1.0 [1.0] 0.019
6 months 2.5 [4.0] 2.0 [1.0] 0.112
12 months 3.5 [4.0] 1.0 [2.0] 0.015
Faecal calprotectin [µg/g]
Baseline 73.0 [1070.5] 38.0 [125.0] 0.782
3 months 201.0 [193.0] 36.0 [67.0] 0.752
6 months 79.0 [331.5] 49.0 [121.0] 0.476
12 months 183.0 [306.5] 30.0 [86.0] 0.373
Infliximab levels [µg/dl]
Baseline 11.9 [9.2] 12.4 [8.7] 0.338
3 months 16.0 [2.6] 16.0 [0.0] 0.431
6 months 16.0 [7.3] 16.0 [0.0] 0.909
12 months 16.0 [2.4] 16.0 [0.0] 0.823

SC, subcutaneous.