. 2022 Mar 19;16(9):1447–1460. doi: 10.1093/ecco-jcc/jjac047

Table 3.

Correlation matrix between calprotectin biomarkers and disease activity.

Disease activity scores^c	CPa9-HNE				Faecal CP				MRP8/14				Neutrophil count				CRP
	CD^b		UC^a		CD^b		UC^a		CD^b		UC^a		CD^b		UC^a		CD^b		UC^a
	r-value	p-value	r-value	p-value	r-value	p-value	r-value	p-value	r-value	p-value	r-value	p-value	r-value	p-value	r-value	p-value	r-value	p-value	r-value	p-value
SES-CD	0.61	<0.0001			0.46	0.0023			0.018	0.89			0.22	0.11			0.29	0.0289
Full Mayo score			0.60	<0.0001			0.53	0.001			0.14	0.41			0.33	0.0343			0.54	0.004
MES			0.53	0.0048			0.33	0.092			0.07	0.68			0.30	0.11			0.42	0.0189
pMayo score			0.51	0.001			0.56	0.0005			0.21	0.21			0.34	0.0342			0.53	0.005
Truelove & Witts			0.63	<0.0001			0.63	<0.0001			0.33	0.0422			0.36	0.0253			0.68	<0.0001
SES-CD	0.39	0.0201			0.35	0.0300			-0.013	0.93			0.27	0.0675			0.29	0.0743
Full Mayo score			0.63	<0.0001			0.49	0.0042			0.18	0.32			0.28	0.12			0.55	0.005
MES			0.57	0.0040			0.35	0.085			0.009	0.96			0.26	0.23			0.41	0.0433
pMayo score			0.51	0.0028			0.49	0.0041			0.22	0.23			0.23	0.20			0.54	0.0009
Truelove & Witts			0.52	0.0035			0.78	<0.0001			0.37	0.047			0.35	0.058			0.72	<0.0001

CD, Crohn’s disease; UC, ulcerative colitis; CP, calprotectin; SES-CD, Simple Endoscopic Score of Severity for CD; MES, Mayo Endoscopic Score; CRP, C-reactive protein.

The biomarker was not normally distributed and the Spearman rho correlation was applied.

The biomarker was normally distributed and the Pearson correlation was applied.

Paired serum and faecal samples.