Table 2. Participant characteristics, hematology results, and mortality.
| True Positive (92) | False Positive and No Growth (938) | Total (1,030) | ||
|---|---|---|---|---|
| Salmonella spp. (51) | Non-Salmonella spp. (41) | |||
| Male, N (%) | 29 (56.9) | 17 (41.5) | 502 (53.9) | 553 (53.7) |
| Median age, years (range, IQR) | 14 (2.5–54, 14.7) | 44 (1–84, 40.0) | 24.6 (1–92, 36.5) | 24 (1–92, 36.2) |
| Mean age, years (SD) | 16.2 (11.1)D,E | 39.6 (24.0)D,F | 28.6 (21.4)E,F | 28.5 (21.4) |
| Distribution of cases by age group, N (%) | ||||
| 1–5 years | 4 (7.8) | 5 (12.2) | 154 (16.4) | 163 (15.8) |
| >5–18 years | 28 (54.9)D,E | 6 (14.6)D | 184 (19.6)E | 218 (21.2) |
| >18–45 years | 18 (35.3) | 11 (26.8) | 365 (38.9) | 394 (38.3) |
| >45–65 years | 1 (2.0)D,E | 13 (31.7)C,D | 179 (19.1)C,E | 193 (18.7) |
| >65 years | 0 (0.0)B,D | 6 (14.6)C,D | 56 (6.0)B,C | 62 (6.0) |
| Days of onset before hospitalization, median (range, IQR) | 7 (1–13, 4) | 4 (1–15, 4) | 4 (1–15, 4) | 4 (1–15, 4) |
| Length of hospitalization, median (range, IQR) | 7 (2–38, 4) | 8 (2–40, 7) | 6 (1–55, 3.3) | 6 (1–55, 4) |
| Received intravenous antibiotics prior to blood collection, N (%) | 9 (17.6)A,E | 16 (39.0)A | 389 (41.5)E | 414 (40.2) |
| Received any antibiotics following blood collection, N (%) | 31/31 (100)E | 18/18 (100)A,C | 199/269 (74.0)A,C,E | 248/318 (77.9) |
| Hematology at enrollment, N (%) | ||||
| Leukopenia | 13/51 (25.5)E | 5/41 (12.2) | 120/937 (12.8)E | 138/1029 (13.4) |
| Normal Leukocyte | 35/51 (68.6)A,E | 19/41 (46.3)A | 462/937 (49.3)E | 516/1029 (50.1) |
| Leukocytosis | 3/51 (5.9)D,E | 17/41 (41.5)D | 355/937 (37.9)E | 375/1029 (36.4) |
| Lymphopenia | 16/44 (36.4)B,D | 26/38 (68.4)D | 442/810 (54.6)B | 484/892 (54.3) |
| Normal Lymphocyte | 17/44 (38.6)A | 7/38 (18.4)A,C | 285/810 (35.2)C | 309/892 (34.6) |
| Lymphocytosis | 11/44 (25.0)E | 5/38 (13.2) | 83/810 (10.2)E | 99/892 (11.1) |
| Outcome, N (%) | ||||
| Died | 3 (5.9)D | 11 (26.8)D,F | 69 (7.4)F | 83 (8.1) |
Study participants with true positive culture results were sub-categorized into Salmonella spp. (consisted of Salmonella enterica serovar Typhi and Paratyphi A) and non-Salmonella spp. groups to better resolve analyses. Comparisons for significance occur across column groups only.
A,B,C indicates p-value <0.05
D,E,F indicates p-value <0.01