Table 1.
Demographic characteristics and comorbidities compared between cohorts with and without erythropoietin treatment in hemodialysis patients in Taiwan.
EPO Users | Non-EPO Users | ||||
---|---|---|---|---|---|
N = 15,992 | N = 15,992 | Standardized | |||
Variable | n | % | n | % | Difference |
Age (year) | |||||
18–40 | 295 | 1.84 | 336 | 2.10 | 0.018 |
41–50 | 928 | 5.80 | 995 | 6.22 | 0.018 |
51–60 | 2293 | 14.3 | 2115 | 13.2 | 0.032 |
61–70 | 3917 | 24.5 | 3742 | 23.4 | 0.026 |
≥71 | 8559 | 53.5 | 8804 | 55.1 | 0.031 |
Gender | |||||
Male | 8119 | 50.8 | 8069 | 50.5 | 0.006 |
Female | 7873 | 49.2 | 7923 | 49.5 | 0.006 |
Urbanization | |||||
Urban | 8459 | 52.9 | 8465 | 52.9 | 0.001 |
Suburban | 5211 | 32.6 | 5206 | 32.6 | 0.001 |
Rural | 2322 | 14.5 | 2321 | 14.5 | 0.000 |
Comorbidity | |||||
Coronary heart disease | 8457 | 52.9 | 8419 | 52.7 | 0.005 |
Hypertension | 14,711 | 92.0 | 14,719 | 92.0 | 0.002 |
Diabetes | 10,839 | 67.8 | 10,830 | 67.7 | 0.001 |
Atrial fibrillation | 1477 | 9.24 | 1435 | 8.97 | 0.009 |
Heart failure | 6796 | 42.5 | 6863 | 42.9 | 0.008 |
Hyperlipidemia | 6956 | 43.5 | 7007 | 43.8 | 0.006 |
Anemia | 9186 | 57.4 | 9230 | 57.7 | 0.006 |
Cataract | 5939 | 37.1 | 6031 | 37.7 | 0.012 |
Diabetic retinopathy | 3575 | 22.4 | 3587 | 22.4 | 0.002 |
Stroke | 6918 | 43.3 | 6900 | 43.2 | 0.002 |
Viral hepatitis | 1545 | 9.66 | 1580 | 9.88 | 0.007 |
DDDs/week, median (IQR) | 2974.7 | (9681.8) | |||
Follow-up years, mean (SD) | 3.97 | (3.61) | 1.02 | (2.10) | 1.000 |
DDDs, defined daily doses; EPO, erythropoietin; IQR, interquartile range; SD, standard deviation.