Table 2.

DEPs generated by mice serum global proteomics validated by PRM.

Protein Accession	Protein Description	Gene Name	Proteomics (Fold Change)		PRM Validation (Fold Change)
			srm_db/srm_bks Ratio	srm_db/srm_bks p Value	srm_db/srm_bks Ratio	srm_db/srm bks p Value
Q9R1P0	Proteasome subunit alpha type-4 OS = Mus musculus OX = 10,090 GN = Psma4 PE = 1 SV = 1	Psma4	1.78	***	2.82	*
O09061	Proteasome subunit beta type-1 OS = Mus musculus OX = 10,090 GN = Psmb1 PE = 1 SV = 1	Psmb1	1.86	***	2.83	**
Q9R1P4	Proteasome subunit alpha type-1 OS = Mus musculus OX = 10,090 GN = Psma1 PE = 1 SV = 1	Psma1	1.95	***	2.38	*
Q9Z2U0	Proteasome subunit alpha type-7 OS = Mus musculus OX = 10,090 GN = Psma7 PE = 1 SV = 1	Psma7	2.04	***	2.29	*
Q91Y97	Fructose-bisphosphate aldolase B OS = Mus musculus OX = 10,090 GN = Aldob PE = 1 SV = 3	Aldob	2.93	***	8.08	*
Q00898	Alpha-1-antitrypsin 1–5 OS = Mus musculus OX = 10,090 GN = Serpina1e PE = 1 SV = 1	Serpina1e	0.14	***	0.01	**
Q60692	Proteasome subunit beta type-6 OS = Mus musculus OX = 10,090 GN = Psmb6 PE = 1 SV = 3	Psmb6	2.01	***	2.99	***
Q9QUM9	Proteasome subunit alpha type-6 OS = Mus musculus OX = 10,090 GN = Psma6 PE = 1 SV = 1	Psma6	2.03	***	3.04	**
Q9R1P1	Proteasome subunit beta type-3 OS = Mus musculus OX = 10,090 GN = Psmb3 PE = 1 SV = 1	Psmb3	2.12	***	3.43	*
P07758	Alpha-1-antitrypsin 1–1 OS = Mus musculus OX = 10,090 GN = Serpina1a PE = 1 SV = 4	Serpina1a	0.47	*	0.46	*

Note: * p < 0.05; ** p < 0.01; *** p < 0.001.