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PIEZO2 upregulation increases lung metastasis of TNBC cells. (A) Tumor growth curves of control (CTRL) and PIEZO2 overexpressed (PIEZO2-OE) MDA-MB-231 in mice. (B) Comparison of primary tumor weight between control and PIEZO2 overexpressed tumors at the endpoint. (C) Representative images of lung metastasis. Scale bar indicates 5 mm. (D) Comparison of lung macrometastatic lesion numbers in control and PIEZO2 overexpressed groups. n = 9, each. * p < 0.05.
