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. 2022 Sep 2;23(17):10019. doi: 10.3390/ijms231710019

Table 1.

Selected significantly enriched gene ontology (GO) terms in clusters 1–5.

Gene Set GO Terms (Biological Function) Adjusted p-Value
DEGs in cluster 1 (n = 353) defense response to virus 0.000
negative regulation of viral process 0.001
negative regulation of viral genome replication 0.000
positive regulation of innate immune response 0.002
leukocyte activation involved in
immune response
0.028
response to type I interferon 0.013
DEGs in cluster 2 (n = 515) mononuclear cell proliferation 0.000
regulation of leukocyte activation 0.000
T-helper 1 type immune response 0.001
positive regulation of cytokine production 0.000
negative regulation of cytokine production 0.031
cellular response to cytokine stimulus 0.000
cytokine-mediated signaling pathway 0.000
tumor necrosis factor superfamily
cytokine production
0.010
positive regulation of apoptotic
signaling pathway
0.035
regulation of apoptotic process 0.000
receptor signaling pathway via STAT 0.000
DEGs in cluster 3 (n = 118) no enriched GO terms
DEGs in cluster 4 (n = 1373) cilium assembly 0.000
cilium movement 0.000
DEGs in cluster 5 (n = 893) epithelial cell proliferation 0.040

DEGs = differentially expressed genes.