Table 1.
Selected significantly enriched gene ontology (GO) terms in clusters 1–5.
Gene Set | GO Terms (Biological Function) | Adjusted p-Value |
---|---|---|
DEGs in cluster 1 (n = 353) | defense response to virus | 0.000 |
negative regulation of viral process | 0.001 | |
negative regulation of viral genome replication | 0.000 | |
positive regulation of innate immune response | 0.002 | |
leukocyte activation involved in immune response |
0.028 | |
response to type I interferon | 0.013 | |
DEGs in cluster 2 (n = 515) | mononuclear cell proliferation | 0.000 |
regulation of leukocyte activation | 0.000 | |
T-helper 1 type immune response | 0.001 | |
positive regulation of cytokine production | 0.000 | |
negative regulation of cytokine production | 0.031 | |
cellular response to cytokine stimulus | 0.000 | |
cytokine-mediated signaling pathway | 0.000 | |
tumor necrosis factor superfamily cytokine production |
0.010 | |
positive regulation of apoptotic signaling pathway |
0.035 | |
regulation of apoptotic process | 0.000 | |
receptor signaling pathway via STAT | 0.000 | |
DEGs in cluster 3 (n = 118) | no enriched GO terms | |
DEGs in cluster 4 (n = 1373) | cilium assembly | 0.000 |
cilium movement | 0.000 | |
DEGs in cluster 5 (n = 893) | epithelial cell proliferation | 0.040 |
DEGs = differentially expressed genes.