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. 2022 Aug 27;23(17):9735. doi: 10.3390/ijms23179735

Figure 5.

Figure 5

Combined treatment of EAA and RET completely restores the loss of mitochondrial biogenesis in skeletal muscle by DEX treatment. (A) Representative image and the proportion of SDH-positive muscle fibers in gastrocnemius (n = 5–6). Scale bar, 200 μm. (B) Representative image and relative protein expression of the PGC1-α in gastrocnemius (n = 5–6). (C) The relative mtDNA copy number with qPCR measurement in gastrocnemius (n = 5–6). Data are presented as mean ± S.E. # Significant difference from control group (p < 0.05). * Significant difference between labeled groups (p < 0.05). CON, sedentary control; DEX, dexamethasone; EAA, essential amino acids; RET, resistance exercise training; SDH, succinate dehydrogenase; PGC1-α, peroxisome proliferator-activated receptor gamma coactivator 1-alpha; mtDNA, mitochondrial DNA.