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. 2022 Aug 24;23(17):9594. doi: 10.3390/ijms23179594

Figure 4.

Figure 4

Principle coordinates analysis (PCoA) plots of all oral microbiome samples based on weighted Unifrac distance. Two-dimensional PCoA plots represent the variation between oral microbiome samples in the dataset as follows (Pre-RT vs. Mid-RT, Pre-RT vs. Post-RT, Mid-RT vs. Post-RT and all the three groups Pre-RT vs. Mid-RT vs. Post-RT). Distances between points on the plot represent how similar samples are in terms of microbiota composition and relative abundance. Therefore, points in the plot that are closer in space are more similar in their taxonomic distribution. Significance differences in the β-diversity were observed for all tested groups except Mid vs. Post. Underlined p values indicate statistical significance (p < 0.05). PC1 and PC2 explained 37% and 27% of the variance. Significance was assessed using PERMANOVA.