Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Polyploidy and overexpressed Myc promote chromatin opening via common effects at high (A) and low (B) levels of organization. A-chromatin opening due to lamina-associated domain detachment from the lamina and chromatin transition from B (closed) to A (open) state. B-chromatin opening due to DNA hypomethylation, histone acetylation, and substitution of canonical histones with non-canonical histone H2A.Z.
