Table 1.
Patients’ characteristics by disease status (relapsed vs. non-relapsed) after first-line treatment.
| Parameter | Exploratory Cohort | Validation Cohort | ||
|---|---|---|---|---|
| Relapsed | Non-Relapsed | Relapsed | Non-Relapsed | |
| Sex, n | ||||
| Male | 5 | 9 | 3 | 7 |
| Female | 2 | 5 | 4 | 7 |
| Age at diagnosis, years a | 15 (11–18) | 16 (10–20) | 16 (7–24) | 15 (7–19) |
| Stage, n | ||||
| II | 3 | 6 | 2 | 4 |
| III | 2 | 5 | 2 | 4 |
| IV | 2 | 3 | 3 | 6 |
| Systemic symptoms, n | ||||
| Yes | 4 | 9 | 2 | 4 |
| No | 3 | 5 | 5 | 10 |
| EBV-positive, n | 2 | 4 | 2 | 4 |
| Treatment level, | ||||
| TL-2 | 3 | 7 | 1 | 3 |
| TL-3 | 4 | 7 | 6 | 11 |
| Response category at ERA b | ||||
| AR | 2 | 9 | 4 | 10 |
| IR | 5 * | 5 | 3 | 4 |
a mean (range); b early response assessment (ERA): AR, adequate response; IR, inadequate response; n.a., not available; * one patient had progression at ERA.