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An illustration of the different ceramides generated either through the de novo synthesis, or the salvage pathway. aCDase: acid ceramidase; nCDase: neutral ceramidase; nSMase: neutral sphingomyelinase; CerS: ceramide synthases; DES1: dihydroceramide desaturase-1; KSR: 3-ketosphinganine reductase; SPT: serine palmitoyltransferase. Created with BioRender.com.
