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. 2022 Aug 30;23(17):9869. doi: 10.3390/ijms23179869

Figure 6.

Figure 6

Network built on the PKH26+, PKH26 and all-samples datasets. (A) Betweenness centrality scores in both PKH26+ (x-axis) and PKH26 (y-axis) networks. “High traffic” genes behaving differently between PKH26+ and PKH26 are highlighted in red. (B) Network visualization from the PKH26+ dataset. Network was built considering as connected only pairs of nodes with extremely elevated correlations (r > |0.98|). See Table S14 for more details. (C) Network visualization from the PKH26 dataset. Network was built considering as connected only pairs of nodes with extremely elevated correlations (r > |0.98|). See Table S15 for more details. (D) Network visualization from the all-samples dataset. Network was built considering as connected only pairs of nodes with extremely elevated correlations (r > |0.98|). See Table S16 for more details. (E) Venn diagram reporting the number of genes identified in the PKH26+ (40 genes) and in the PKH26 network (61 genes), and in both PKH26+ and PKH26 networks (49 genes). Networks were built considering as connected only pairs of nodes with extremely elevated correlations (r > |0.98|). Statistical significance of the overlap: p-value < 1 × 10−4; RR = 3.6.