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Exercise enhances AMPK activity in mouse brain tissue. Relative protein levels of (A) AMPK and (B) p-AMPK in brain tissue (n = 6). The relative expression levels of (C) APPL1 and (D) LKB1 mRNA in brain tissue were measured by RT-PCR (n = 5). Data are presented as means ± SDs. # p < 0.05 vs. WT + SED mice, * p < 0.05, and ** p < 0.01 vs. AP + SED mice.
