Table 1.

Potential molecular biomarkers for differential diagnosis between uterine LMSand UFs.

Molecular Biomarker	Reference
MED12 gene mutations in leiomyosarcoma	Bertch et al. [29]
Progesterone and estrogen receptor under-expression in uterine leiomyosarcoma	Zhang et al. [31]
TOP2A gene overexpression in leiomyosarcoma	Baiocchi et al. [32]
CHI3L1, MELK, PRC1, TOP2A andTPX2 gene overexpression In uterine leiomyosarcoma	Adams et al. [33]
DNA fragmentation factors 40 and 45 (DFF40 and DFF45 and Bcl-2 (B-cell lymphoma 2) under-expression in uterine leiomyosarcoma	Banas et al. [34]
miRNAs (miR-1246 and miR-191-5p) in leiomyosarcoma	Yokoi et al. [35]
STMN1 and MKI67 micro RNA are overexpressed in uterine LMS	Hu et al. [36]
let-7family micro RNA is downregulated in uterine leiomyosarcoma	De Almeida et al. [37]