Figure 2.

Histology of head sections of adult male transgenic zebrafish (two years old). Hematoxylin-eosin-stained tissue sections of transgenic zebrafish with (A) bilateral or (B) unilateral macroscopic ocular alterations. (C) Control tissue sections from wild-type zebrafish of the same age and sex. Black arrows: contacts between iris and cornea; black arrowheads: increased thickness of the corneal stroma; black asterisks: increased vitreous-like material; green arrows: folded and thickened lens capsule; blue arrowhead: overgrowth and folding of the retina; red asterisk: displaced lens: white arrows: hypertrophy of the retinal fiber layer and optic nerve; yellow arrowheads: abnormal photoreceptors; yellow asterisks: overgrowth of the choroid body. Scale bar: 800 µm. Cor: cornea; OA: ocular alterations; ON: optic nerve; L: lens; R: retina; +/+: wild type; Tg/+: transgenic.