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. 2022 Aug 29;23(17):9777. doi: 10.3390/ijms23179777

Figure 5.

Figure 5

Selected genetic risk factors for late-onset Alzheimer’s disease. Genes associated with a risk of Alzheimer’s disease are involved in lipid metabolism, the immune system and inflammation, or synaptic plasticity and synaptic cell functioning. APOE, apolipoprotein E gene; CLU, clusterin gene; ABCA7, ATP-binding cassette transporter A7 gene; ABCA1, ATP-binding cassette transporter A1 gene; CR1, complement C3b/C4b receptor 1 gene; EPHA1, ephrin type-A receptor 1 gene; MS4A, membrane-spanning 4A gene; TREM2, triggering receptor expressed on myeloid cells 2 gene; PICALM, phosphatidylinositol binding clathrin assembly protein gene; BIN1, bridging integrator 1 gene; SORL1, sorting protein-related receptor gene; CDA2P, CD2-associated protein gene; PSEN1/2, presenilin 1 or 2 gene; RIN3, Ras and Rab interactor 3 gene; CD33, sialic acid binding Ig-like lectin 3 gene. Created with Biorender.com.