Table 1.
PCD 1 Group N = 17 |
Control Group N = 17 |
p-Value | |
---|---|---|---|
Age, median (Q1–Q3) | 39 (33–54) | 39 (33–54) | 0.89 |
Gender male, n (%) | 8 (47%) | 6 (35%) | 0.49 |
Ciliary ultrastructure defect, n (%) | |||
nEM 2 | 5 (29%) | 17 (100%) | - |
IDA + MTD 3 | 3 (18%) | 0 | - |
ODA 4 | 6 (35%) | 0 | - |
IDA + ODA | 3 (18%) | 0 | - |
CC 5 | 0 | 0 | - |
Kartagener syndrome, n (%) | 3 (18%) | 0 | 0.22 |
Consanguinities, n (%) | 8 (47%) | 3 (18%) | 0.07 |
Otitis media history, n (%) | 10 (59%) | 3 (18%) | 0.01 |
Rhinosinusitis history, n (%) | 17 (100%) | 13 (76%) | 0.1 |
CRSwNP 6, n(%) | 7 (41%) | 2 (12%) | 0.1 |
SNOT-22 7 score, median (Q1–Q3) | 58 (46.5–69) | 33.5 (14.2–46) | 0.01 |
Sinus hypo or aplasia, n (%) | 15 (88%) | 3 (18%) | 0.0001 |
Modified Lund–Mackay score, median (Q1–Q3) | 13.5 (10–19.2) | 6 (2.7–10.2) | 0.01 |
1 Primary ciliary dyskinesia; 2 normal electronic microscopy; 3 inner dynein arm defects with microtubular disorganization; 4 outer dynein arm defects; 5 central complex defects, 6 chronic rhinosinusitis with nasal polyps, 7 sinonasal outcome test-22.