Table 19.
Physico-chemical properties and biological data obtained for compound 8a [139].
| 8a | |
|---|---|
| λabs a | 664 nm |
| λem a | 768 nm |
| Φfluo b | 0.052 |
| 1O2 QY c | 0.018 |
| IC50 (HeLa) d | 0.67 μM |
| IC50 (A549) d | 0.44 μM |
| IC50 (H22) d | 0.48 μM |
a In DMF. b Relative to unsubstituted zinc(II) phthalocyanine in DMF as the reference (Φfluo ≈ 0.28). c Relative to unsubstituted zinc(II) phthalocyanine (1O2 QY ≈ 0.56). d Irradiation with a 670 nm LED lamp for 2 min with an irradiance of 20 mW/cm2.