Table 3.
Formulation Code | Hardness (kg/F) | Friability % | Disintegration (min) |
---|---|---|---|
F1 | 2.8 ± 3.2 | 2.84 ± 0.03 | 0.82 ± 0.20 |
F2 | 2.5 ± 3.4 | 2.12 ± 0.02 | 1.15 ± 0.14 |
F3 | 3.1 ± 2.1 | 1.60 ± 0.04 | 1.20 ± 0.17 |
F4 | 3.8 ± 2.7 | 1.25 ± 0.05 | 4.12 ± 0.38 |
F5 | 4.7 ± 3.2 | 0.85 ± 0.01 | 4.92 ± 0.25 |
F6 | 5.4 ± 2.0 | 0.68 ± 0.06 | 5.21 ± 0.44 |
F7 | 5.8 ± 2.6 | 0.60 ± 0.01 | 5.70 ± 0.32 |
F8 | 7.1 ± 3.0 | 0.48 ± 0.02 | 6.55 ± 0.30 |
F9 | 8.7 ± 2.1 | 0.32 ± 010 | 8.24 ± 0.56 |
F1 = CAC at 56.64 Mnm−2 compression pressure, F2 = CAC at 84.96 Mnm−2 compression pressure, F3 = CAC at 113.28 Mnm−2 compression pressure, F4 = C-MCC at 56.64 Mnm−2 compression pressure, F5 = C-MCC at 84.96 Mnm−2 compression pressure, F6 = C-MCC at 113.28 Mnm−2 compression pressure, F7 = AV at 56.64 Mnm−2 compression pressure, F8 = AV at 84.96 Mnm−2 compression pressure, F9—AV at 113.28 Mnm−2 compression pressure.