Table 3.
Comparison of routine laboratory parameters between ILD progressors and non progressors.
| ILD Progressors (N = 19) | ILD Non Progressors (N = 121) | p | |
|---|---|---|---|
| White blood cells G/L | 7.4 (5.8; 9.1) | 7.1 (5.8; 8.8) | 0.69 |
| Monocytes G/L | 0.7 (0.6; 1.0) | 0.6 (0.5; 0.8) | 0.028 |
| Neutrophils G/L | 4.5 (3.3; 6.4) | 4.4 (3.5; 5.6) | 0.90 |
| Eosinophils G/L | 0.2 (0.1; 0.2) | 0.2 (0.1; 0.3) | 0.93 |
| Lymphocytes G/L | 1.6 (1.2; 2.0) | 1.6 (1.2; 2.3) | 1.00 |
| Basophils G/L | 0.0 (0.0; 0.1) | 0.0 (0.0; 0.1) | 0.59 |
| Hemoglobin g/dL | 13.9 (12.8; 14.7) | 13.1 (12.4; 14.2) | 0.12 |
| Platelets G/L | 243.0 (221.0; 291.5) | 273.0 (230.0; 314.0) | 0.60 |
| CRP mg/L | 4.0 (3.0; 5.0) | 3.0 (3.0; 5.0) | 0.29 |
| ESR mm/h | 9.0 (5.5; 22.0) | 10.0 (6.0; 22.0) | 0.93 |
| NT pro BNP ng/L | 113.0 (67.0; 291.0) | 97.0 (55.0; 248.0) | 0.51 |
| Ferritin ng/mL | 99.0 (61.5; 151.0) | 70.0 (29.0; 129.0) | 0.094 |
| Uric acid mg/L | 48.0 (40.0; 59.0) | 46.5 (35.0; 56.0) | 0.59 |
| AST UI/L | 23.0 (19.5; 28.5) | 21.0 (18.0; 25.0) | 0.37 |
| ALT UI/L | 18.0 (13.5; 22.5) | 16.0 (12.0; 22.0) | 0.59 |
| ALP UI/L | 58.0 (52.5; 94.5) | 62.0 (52.0; 79.0) | 0.90 |
| GGT UI/L | 29.0 (22.0; 50.0) | 21.5 (15.0; 43.0) | 0.13 |
| Total bilirubin mg/L | 4.5 (3.0; 6.5) | 3.0 (3.0; 5.0) | 0.099 |
| Serum sodium mmol/L | 140.0 (139.0; 141.0) | 140.0 (139.0; 141.0) | 0.95 |
| Serum potassium mmol/L | 4.2 (4.0; 4.4) | 4.2 (4.0; 4.5) | 0.37 |
| Urea g/L | 0.3 (0.3; 0.4) | 0.3 (0.3; 0.4) | 0.70 |
| Creatinin mg/L | 8.0 (7.0; 9.0) | 8.0 (7.0; 9.0) | 0.89 |
| A1globulins g/L | 3.0 (2.8; 3.4) | 3.0 (2.6; 3.3) | 0.45 |
| A2globulins g/L | 8.0 (7.4; 8.6) | 7.7 (6.9; 8.4) | 0.64 |
| Beta globulins g/L | 7.5 (6.8; 8.3) | 7.8 (7.2; 8.4) | 0.29 |
| Gamma globulins g/L | 9.0 (8.0; 10.3) | 10.1 (7.9; 12.2) | 0.24 |
| Albumin g/L | 40.2 (38.0; 43.1) | 40.1 (38.0; 43.1) | 0.54 |
Values are presented as median (interquartile range); CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; ALP: alkaline phosphatase; AST: aspartate aminotransferase; ALT: alanine aminotransferase; GGT: gammaglutamyltranspeptidase; NTproBNP: N-terminal pro-brain natriuretic peptide; G/L: Giga/Liter. p value < 0.05 (significant results appear in bold in the table). A1 globulins: alpha 1 globulins; A2 globulins: alpha 2 globulins; 6 patients had a missing FVC value (1 at baseline and 5 at follow up) precluding their classification as either progressors or non progressors.