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. 2022 Sep 2;11(17):5204. doi: 10.3390/jcm11175204

Table 1.

Characteristics of general population, and separately for atopic dermatitis (AD) and non-AD.

General Population AD Population Non-AD Population p-Value *
Patients N tot 641 284 357
Males n (%) 246 (38.4) 96 (33.8) 150 (42.0) 0.033
Age (mean ± SD) 46.2 ± 19.4 36.9 ± 16.4 53.7 ± 17.9 <0.0001
BMI (mean ± SD) 24.3 ± 4.4 23.5 ± 4.4 25.1 ± 0.23 <0.0001
Previous diagnosis of AD n (%) 362 (56.5) 219 (77.1) 126 (35.3) <0.0001
Disease duration (mean ± SD) 10.7 ± 11.8 15.3 ± 12.6 7.0 ± 9.7 <0.0001
Family history of AD n (%) 115 (17.9) 66 (23.2) 47 (13.1) <0.0001
Family history of other atopic comorbidities n (%) 183 (28.5) 109 (38.4) 72 (20.2) <0.0001
Job Title
Intellectual jobs (white collars) n (%) 260 (40.6) 124 (43.7) 136 (38.1) 0.176
Manual jobs (blue collars) n (%) 154 (24.0) 78 (27.5) 76 (21.3) 0.069
Physicians Previously Consulted
Dermatologist n (%) 542 (84.5) 264 (93.0) 278 (77.9) <0.0001
Allergologist n (%) 219 (34.2) 139 (48.9) 80 (22.4) <0.0001
General practitioner n (%) 39 (6.1) 6 (2.1) 33 (9.2) <0.0001
Patient’s Related Outcomes
Itch intensity (mean, SD) 6.5 ± 2.5 6.9 ± 2.4 6.2 ± 2.6 0.0003
Interference with sleep (mean ± SD) 4.4 ± 3.4 5.0 ± 3.4 3.9 ± 3.4 <0.0001
Interference with work (mean ± SD) 3.7 ± 3.4 4.3 ± 3.5 3.4 ± 3.4 0.002
Interference with sport (mean ± SD) 3.4 ± 3.4 4.1 ± 3.4 2.8 ± 3.2 <0.0001
Disease induced embarassment (mean ± SD) 5.7 ± 3.2 6.4 ± 2.9 5.1 ± 3.3 <0.0001
Treatments Routinely Used
Topical compounds n (%) 259 (40.4) 126 (44.3) 133 (37.2) <0.0001
Moisturizers n (%) 294 (45.8) 160 (56.3) 134 (37.5) <0.0001
Systemic therapies n (%) 41 (6.4) 20 (7.0) 21 (5.9) 0.07
No treatments n (%) 225 (35.1) 90 (31.7) 135 (37.9) <0.0001

Legend. Categorical data expressed as n (%); continuous data expressed as mean ± standard deviation * p value refers to the comparison between AD and non-AD population.