Table 3.
Accuracy of the LIAISON® Meridian H. pylori SA test in post-treatment patients.
| Comparison SAT vs. UBT | Sensitivity (95% CI) |
Specificity (95% CI) |
PPV (95% CI) |
NPV (95% CI) |
LR+ (95% CI) |
LR− (95% CI) |
Global Accuracy (95% CI) |
AUC (95% CI) |
|---|---|---|---|---|---|---|---|---|
| Post-treatment | 55% (31–78) | 98% (95–100) | 80% (56–100) | 93% (89–98) | 25 (8–82) | 0.46 (0.29–0.73) | 92% (87–96) | 0.79 (0.65–0.93) |
| NDIRS post-treatment | 53 % (26–80) | 99% (96–100) | 90% (66–100) | 91% (85–98) | 46 (6–336) | 0.48 (0.29–0.79) | 91% (85–97) | 0.81 (0.67–0.95) |
| IRMS post-treatment | 60% (7–100) | 96% (90–100) | 60% (7–100) | 96% (90–100) | 16 (3–75) | 0.42 (0.14–1.22) | 93% (86–100) | 0.78 (0.44–1.0) |
SAT: stool antigen test; UBT: urea breath test; PPV: positive predictive value; NPV: negative predictive value; LR+: positive likelihood ratio; LR−: negative likelihood ratio; AUC: area under the ROC curve; IRMS: isotope ratio mass spectrometry, cut-off value 5‰; NDIRS: non-dispersive isotope-selective infrared spectrometry, cut-off value 2.5‰.