Table 2.
Characteristics of eligible studies. BMI, body mass index; CI, confidence interval; FVC, forced vital capacity; IQR, interquartile range; IPF, idiopathic pulmonary fibrosis; ND, no data available; OSA, obstructive sleep apnea. IPF severity was assessed using FVC% predicted.
| Paper | Year | Mean/Median Age of IPF Patients | Mean/Median BMI | IPF–Total | IPF Severity (FVC% Predicted) | IPF–OSA | Referral OSA Prevalence in Ethnically Matched Population | Mean/Median Age of General Population Study | Reference to OSA Prevalence |
|---|---|---|---|---|---|---|---|---|---|
| Lancaster et al. [5] | 2009 | 64.9 | 32.3 | 50 | ND | 44.0 (88.0%) | 3.4% | 58.0 | [48] |
| Mermigkis et al. [33] | 2010 | 65 ± 10.6 | 27.3±4.0 | 34 | 72.5±18.1 | 20.0 (58.8%) | 26.8% | 54.1 ± 16.1 | [49] |
| Pillai et al. [34] | 2012 | 69.2 ± 7.0 | 30.4 ± 6.9 | 54 | 64.0 ± 15.9 | 35.0 (64.8%) | 3.4% | 58.0 | [48] |
| Kolilekas et al. [35] | 2013 | 67.96 ± 7.88 | 28,7 ± 4.3 | 31 | 77.6 ± 17.1 | 28.0 (90.3%) | 26.8% | 54.1 ± 16.1 | [49] |
| Pihtiliet al. [31] | 2013 | 60.94 ± 8.11 | 26.4±2.0 | 17 | 79.0 ± 23.9 | 14.0 (82.4%) | 13.7% | 40.7 ± 15.1 | [50] |
| Lee et al. [36] | 2015 | 67.9 ± 12.3 | 28.5 ± 4.6 | 20 | 82.2 ± 15.3 | 9.0 (45.0%) | 3.4% | 58.0 | [48] |
| Mermigkiset al. [32] | 2015 | 70.3 ± 7.9 | ND | 92 | ND | 78.0 (84.0%) | 26.0% | 54.1 ± 16.1 | [49] |
| Schertel et al. [37] | 2017 | 67.0 (IQR: 60.0–77.0) | 24.9 (IQR: 24.0–29.8) | 9 | 58 (IQR: 56–77) | 6.0 (66.7%) | 19.0% | 57.0 (IQR: 49.0–68.0) | [51] |
| Bosi et al. [38] | 2017 | 68.7 ± 9.2 | 22.7 ± 3.7 | 35 | 72.2 ± 19.6 | 25.9 (71.4%) | 72.0% | 40.0–85.0 | [52] |
| Gille et al. [39] | 2017 | 68.8 ± 8.7 | 28 ± 3.5 | 45 | 72.8 ± 20.3 | 40.0 (88.9%) | 4.9% | 46.8 | [53] |
| Cardoso et al. [40] | 2018 | >60.0 | <30.0 | 12 | 86.1 ± 18.9 | 10.0 (83.3%) | 0.9% | 62.8 (95%CI: 61.6–64.1) | [54] |
| Mavroudi et al. [41] | 2018 | 69.8 ± 8.1 | 29.2 ± 5.3 | 19 | 75.6 ± 16.2 | 15.0 (79.0%) | 26.8% | 54.10 ± 16.1 | [49] |
| Canora et al. [42] | 2019 | 69 ± 7.8 | 28.7 | 54 | 71.5 ± 23.2 | 42.0 (77.8%) | 72.0% | 40.0–85.0 | [52] |
| Tudorache et al. [43] | 2019 | 67.6 ± 8.7 | 27.7 ± 4.5 | 23 | 71.3 ± 16.4 | 19.0 (82.6%) | 6.4% | >18.0 | [55] |
| Sarac et al. [44] | 2019 | 62.0 ± 9.4 | 27.9 ± 4.8 | 16 | 71.0 (62.0–85.3) | 12.0 (75.0%) | 13.7% | 40.7 ± 15.1 | [50] |
| Pereira et al. [45] | 2019 | 67.16 ± 12.18 | 25.6 ± 2.9 | 12 | 86.1 ± 18.9 | 10.0 (83.3%) | 0.9% | 62.8 (95% CI: 61.6–64.1) | [54] |
| Bosi et al. [46] | 2019 | 69.7 (IQR: 64.8–74.7) | 21.9 | 34 | 75.5 (IQR: 56.8–87.0) | 25.0 (73.5%) | 72.0% | 40.0–85.0 | [52] |
| Lee et al. [47] | 2020 | 72.5 ± 7.2 | 24.1 ± 3.6 | 57 | 72.4 ± 14.8 | 37.0 (64.9%) | 23.0% | 49.6 ± 7.7 | [56] |