FIG. 6.

Alignment of amino acid sequences for representative homologs of the P. aeruginosa phosphogluconolactonase. The homologs were identified using the BLAST program and were aligned with Genetics Computer Group programs. The consensus sequence was generated using a plurality of five. The sequences include the PAO-derived sequence reported here, and ones from Helicobacter pylori (GenBank accession no. AE000616), Anabaena (Swiss-Prot. accession no. P46016), Synechocystis sp. strain PCC6083 (DDBJ accession no. D90916), Actinobacillus actinomycetemcomitans (DDBJ accession no. D88189), H. influenzae (Swiss-Prot. accession no. Q57039), Treponema pallidum (GenBank accession no. AAC65464), and S. cerevisiae SOL1 (Swiss-Prot. accession no. P50278). Sequence numbers refer to the S. cerevisiae SOL1 amino acid sequence (residues 1 to 30 not shown). Additional N-terminal sequence for the H. influenzae homolog (underlined) was deduced from the DNA sequence (12).