Aβ |
amyloid-β |
AD |
Alzheimer’s disease |
Akt |
protein kinase B |
AMPK |
5'AMP-activated protein kinase |
AP |
1-activator protein-1 |
Ara4N |
4-amino-arabinose |
BAY61-3606 |
2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino] pyridine-3-carboxamide |
BBB |
blood–brain barrier |
CARD |
caspase recruitment domain |
CD-14 |
cluster of differentiation-14 |
CD-36 |
cluster of differentiation-36 |
CGRP |
calcitonin gene-related peptide |
CNS |
central nervous system |
COX |
cyclooxygenase |
CR |
complement receptor |
CREB |
cAMP-response element binding protein |
C1q |
complement component 1q |
DAMP |
damage-associated molecular pattern |
DYRK1A |
tyrosine phosphorylation regulated kinase 1A |
FDA |
Food and Drug Administration |
GC |
glucocorticoid |
GSDMD |
gasdermin-D |
GSK3 |
glycogen synthase kinase 3 |
GTS-21 |
3-(2,4-dimethoxybenzylidene)-anabaseine, DMXBA |
Iba-1 |
ionized calcium-binding adaptor molecule 1 |
IKK |
Iκβ kinase complex |
IKKi |
IKK inducible kinase |
IL |
interleukin |
iNOS |
inducible nitric oxide synthase |
IRAK |
interleukin-1 receptor associated kinase |
IRF |
interferon regulatory factor |
LBP |
lipopolysaccharide-binding protein |
LPS |
lipopolysaccharide |
LRR |
leucine-rich repeat domain |
MAL |
MyD88- adopter-like protein |
MAPK |
mitogen-activated protein kinase |
MIP |
macrophage inflammatory protein |
MWM |
Morris water maze test |
MyD88 |
myeloid differentiation primary response protein |
NAD |
novel arm discrimination task |
NEMO |
NF-κB essential modulator |
NF-κB |
nuclear factor-Κb |
NFT |
intracellular neurofibrillary tangles |
NLRP3 |
NLR family pyrin domain containing 3 |
NLR |
NOD-like receptor |
NMDA |
N-methyl-D-aspartate |
NO |
nitric oxide |
NOR |
novel object recognition task |
NSAID |
non-steroidal anti-inflammatory drug |
OFT |
open field task |
PAMP |
pathogen-associated molecular pattern |
PAR1 |
protease-activated receptor 1 |
PAT |
passive avoidance test |
PD |
Parkinson’s disease |
PGE2
|
prostaglandin E2
|
PPAR-γ |
peroxisome proliferator- activated receptor gamma |
PRR |
pattern recognition receptor |
PT |
pole test |
RAGE |
receptor for advanced glycation end-products |
RIP1/RIPK1 |
receptor-interacting serine/threonine-protein kinase 1 |
RLR |
retinoic acid inducible gene-I-like receptor |
ROS |
reactive oxygen species |
SN |
substantia nigra |
SNpc |
substantia nigra pars compacta |
SR |
scavenger receptor |
SP |
substance P |
TAB |
TAK1 binding protein |
TAK1 |
transforming growth factor β-activated kinase 1 |
TBK1 |
TANK-binding kinase 1 |
TIR |
Toll/IL-1 receptor domain |
TIRAP |
TIR domain containing adaptor protein |
TNF-α |
tumor necrosis factor-α |
TLR |
Toll-like receptor |
TRAF |
TNF-receptor associated factor |
TRAM |
TRIF-related adaptor molecule |
TRIF |
Toll/interleukin-1-receptor domain- containing adaptor inducing interferon β |
TRP |
transient receptor potential |
TRPA1 |
transient receptor potential ankyrin 1 |
TRPM3 |
transient receptor potential melastatin 3 |
TRPM8 |
transient receptor potential melastatin 8 |
TRPV1 |
transient receptor potential cation channel subfamily V member 1 |
TRPV4 |
transient receptor potential vanilloid 4 |
TSPO |
translocator protein |
WHO |
World Health Organization |