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. 2022 Aug 26;27(17):5481. doi: 10.3390/molecules27175481
amyloid-β
AD Alzheimer’s disease
Akt protein kinase B
AMPK 5'AMP-activated protein kinase
AP 1-activator protein-1
Ara4N 4-amino-arabinose
BAY61-3606 2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino] pyridine-3-carboxamide
BBB blood–brain barrier
CARD caspase recruitment domain
CD-14 cluster of differentiation-14
CD-36 cluster of differentiation-36
CGRP calcitonin gene-related peptide
CNS central nervous system
COX cyclooxygenase
CR complement receptor
CREB cAMP-response element binding protein
C1q complement component 1q
DAMP damage-associated molecular pattern
DYRK1A tyrosine phosphorylation regulated kinase 1A
FDA Food and Drug Administration
GC glucocorticoid
GSDMD gasdermin-D
GSK3 glycogen synthase kinase 3
GTS-21 3-(2,4-dimethoxybenzylidene)-anabaseine, DMXBA
Iba-1 ionized calcium-binding adaptor molecule 1
IKK Iκβ kinase complex
IKKi IKK inducible kinase
IL interleukin
iNOS inducible nitric oxide synthase
IRAK interleukin-1 receptor associated kinase
IRF interferon regulatory factor
LBP lipopolysaccharide-binding protein
LPS lipopolysaccharide
LRR leucine-rich repeat domain
MAL MyD88- adopter-like protein
MAPK mitogen-activated protein kinase
MIP macrophage inflammatory protein
MWM Morris water maze test
MyD88 myeloid differentiation primary response protein
NAD novel arm discrimination task
NEMO NF-κB essential modulator
NF-κB nuclear factor-Κb
NFT intracellular neurofibrillary tangles
NLRP3 NLR family pyrin domain containing 3
NLR NOD-like receptor
NMDA N-methyl-D-aspartate
NO nitric oxide
NOR novel object recognition task
NSAID non-steroidal anti-inflammatory drug
OFT open field task
PAMP pathogen-associated molecular pattern
PAR1 protease-activated receptor 1
PAT passive avoidance test
PD Parkinson’s disease
PGE2 prostaglandin E2
PPAR-γ peroxisome proliferator- activated receptor gamma
PRR pattern recognition receptor
PT pole test
RAGE receptor for advanced glycation end-products
RIP1/RIPK1 receptor-interacting serine/threonine-protein kinase 1
RLR retinoic acid inducible gene-I-like receptor
ROS reactive oxygen species
SN substantia nigra
SNpc substantia nigra pars compacta
SR scavenger receptor
SP substance P
TAB TAK1 binding protein
TAK1 transforming growth factor β-activated kinase 1
TBK1 TANK-binding kinase 1
TIR Toll/IL-1 receptor domain
TIRAP TIR domain containing adaptor protein
TNF-α tumor necrosis factor-α
TLR Toll-like receptor
TRAF TNF-receptor associated factor
TRAM TRIF-related adaptor molecule
TRIF Toll/interleukin-1-receptor domain- containing adaptor inducing interferon β
TRP transient receptor potential
TRPA1 transient receptor potential ankyrin 1
TRPM3 transient receptor potential melastatin 3
TRPM8 transient receptor potential melastatin 8
TRPV1 transient receptor potential cation channel subfamily V member 1
TRPV4 transient receptor potential vanilloid 4
TSPO translocator protein
WHO World Health Organization