| Aβ | amyloid-β |
| AD | Alzheimer’s disease |
| Akt | protein kinase B |
| AMPK | 5'AMP-activated protein kinase |
| AP | 1-activator protein-1 |
| Ara4N | 4-amino-arabinose |
| BAY61-3606 | 2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino] pyridine-3-carboxamide |
| BBB | blood–brain barrier |
| CARD | caspase recruitment domain |
| CD-14 | cluster of differentiation-14 |
| CD-36 | cluster of differentiation-36 |
| CGRP | calcitonin gene-related peptide |
| CNS | central nervous system |
| COX | cyclooxygenase |
| CR | complement receptor |
| CREB | cAMP-response element binding protein |
| C1q | complement component 1q |
| DAMP | damage-associated molecular pattern |
| DYRK1A | tyrosine phosphorylation regulated kinase 1A |
| FDA | Food and Drug Administration |
| GC | glucocorticoid |
| GSDMD | gasdermin-D |
| GSK3 | glycogen synthase kinase 3 |
| GTS-21 | 3-(2,4-dimethoxybenzylidene)-anabaseine, DMXBA |
| Iba-1 | ionized calcium-binding adaptor molecule 1 |
| IKK | Iκβ kinase complex |
| IKKi | IKK inducible kinase |
| IL | interleukin |
| iNOS | inducible nitric oxide synthase |
| IRAK | interleukin-1 receptor associated kinase |
| IRF | interferon regulatory factor |
| LBP | lipopolysaccharide-binding protein |
| LPS | lipopolysaccharide |
| LRR | leucine-rich repeat domain |
| MAL | MyD88- adopter-like protein |
| MAPK | mitogen-activated protein kinase |
| MIP | macrophage inflammatory protein |
| MWM | Morris water maze test |
| MyD88 | myeloid differentiation primary response protein |
| NAD | novel arm discrimination task |
| NEMO | NF-κB essential modulator |
| NF-κB | nuclear factor-Κb |
| NFT | intracellular neurofibrillary tangles |
| NLRP3 | NLR family pyrin domain containing 3 |
| NLR | NOD-like receptor |
| NMDA | N-methyl-D-aspartate |
| NO | nitric oxide |
| NOR | novel object recognition task |
| NSAID | non-steroidal anti-inflammatory drug |
| OFT | open field task |
| PAMP | pathogen-associated molecular pattern |
| PAR1 | protease-activated receptor 1 |
| PAT | passive avoidance test |
| PD | Parkinson’s disease |
| PGE2 | prostaglandin E2 |
| PPAR-γ | peroxisome proliferator- activated receptor gamma |
| PRR | pattern recognition receptor |
| PT | pole test |
| RAGE | receptor for advanced glycation end-products |
| RIP1/RIPK1 | receptor-interacting serine/threonine-protein kinase 1 |
| RLR | retinoic acid inducible gene-I-like receptor |
| ROS | reactive oxygen species |
| SN | substantia nigra |
| SNpc | substantia nigra pars compacta |
| SR | scavenger receptor |
| SP | substance P |
| TAB | TAK1 binding protein |
| TAK1 | transforming growth factor β-activated kinase 1 |
| TBK1 | TANK-binding kinase 1 |
| TIR | Toll/IL-1 receptor domain |
| TIRAP | TIR domain containing adaptor protein |
| TNF-α | tumor necrosis factor-α |
| TLR | Toll-like receptor |
| TRAF | TNF-receptor associated factor |
| TRAM | TRIF-related adaptor molecule |
| TRIF | Toll/interleukin-1-receptor domain- containing adaptor inducing interferon β |
| TRP | transient receptor potential |
| TRPA1 | transient receptor potential ankyrin 1 |
| TRPM3 | transient receptor potential melastatin 3 |
| TRPM8 | transient receptor potential melastatin 8 |
| TRPV1 | transient receptor potential cation channel subfamily V member 1 |
| TRPV4 | transient receptor potential vanilloid 4 |
| TSPO | translocator protein |
| WHO | World Health Organization |