Figure 2.

Myrcene, linalool, limonene andα-pinene do not alter cannabinoid signaling in autaptic hippocampal neurons. (A) Myrcene (1 µM) did not alter EPSCs. (B) Myrcene also did not have an effect on DSE responses. (C) Linalool (1 µM) slightly increased EPSCs. (D) However, linalool had no effect on DSE responses. (E) Limonene (1 µM) did not alter EPSC sizes (F) and did not significantly inhibit DSE responses. (G) α-pinene (1 µM) did not alter EPSCs. (H) Similarly α-pinene did not inhibit DSE responses. * p < 0.05 one-sample t-test vs. 1.0 or vs. baseline at 3 s of depolarization. Mean ± SEM shown.