Table 1.
Effective dose 50 (ED50, with 95% confidence interval) calculated from depolarization-response curves indicates the duration of depolarization (in sec) necessary to produce 50% maximal response. Maximal inhibition shows relative EPSC values at the longest depolarization (10 s, 1.0 = no inhibition).
| Terpenoid | Control | |||||
|---|---|---|---|---|---|---|
| ED50 (sec) | 95% CI | Max. Inhibition | ED50 (sec) | 95% CI | Max. Inhibition | |
| Myrcene | 3.50 | 0.3–32.2 | 0.50 | 1.14 | 0.67–5.19 | 0.49 |
| Linalool | 31.31 | ambiguous | 0.59 | 22.1 | ambiguous | 0.51 |
| Limonene | 8.59 | 1.6–46.1 | 0.60 | 3.24 | 1.5–7.1 | 0.48 |
| α-pinene | 1.60 | 0.88-2.88 | 0.79 | 1.45 | 0.36-5.82 | 0.58 |
| Nerolidol (100 nM) | 3.33 | ambiguous | 0.64 | 2.28 | 1.15–110.7 | 0.56 |
| Nerolidol (1 μM) | 6.97 | ambiguous | 0.81 | 1.32 | 0.68–23.22 | 0.49 |