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. 2022 Sep 5;27(17):5721. doi: 10.3390/molecules27175721

Table 2.

The IC50 (µg/mL) for PGEO against DPPH, lipase, α-amylase, α-glucosidase, COX-1, and COX-2, as well for the positive controls.

Antioxidants, Target Metabolic Enzymes, Cancer Cells Lines, and COX IC50 (µg/mL)
PGEO Positive Controls
DPPH 3.88 ± 0.45 1.88 ± 0.45 a
Lipase 478.14 ± 1.2 12.3 ± 0.33 b
α-Amylase 66.09 ± 1.43 6.64 ± 0.32 c
α-Glucosidase 52.44 ± 0.29 37.15 ± 0.33 c
HeLa 315.19 ± 2.05 0.84 ± 1.1 d
MCF7 32.71 ± 1.25 0.37 ± 0.22 d
Hep3B 40.70 ± 1.89 1.21 ± 1.0 d
COX-1 14.03 ± 1.74 5.72 ± 0.09 e
COX-2 275.97 ± 2.08 0.0152 ± 0.007 e

a Trolox, b Orlistat, c Acarbose, d Doxorubicin, and e Celecoxib.