Table 1.
Summary of various Fe-HNPs for cancer imaging and theranostics.
| Material | Size (nm) | Templates and Mechanisms | Biomedical Applications | Reference |
|---|---|---|---|---|
| HPIOs-14@ZDS | 14 | Mn3O4 | T1-weighted MRI | [58] |
| 7-Fe3O4@ZDS | 7 | – | T1-weighted MRI | [75] |
| HMNPs | 120 | SiO2 | T2-weighted MRI | [76] |
| PeA@OSNC | 82 | – | T2-weighted MRI | [78] |
| HMNC | 150−200 | Self-assembly | T2-weighted MRI | [77] |
| ipGdIO | 160 | – | T1-/T2-weighted MRI | [81] |
| HMON2@FG3 | 47.8 | SiO2 | T1-/T2-weighted MRI | [82] |
| Gd–Fe/HCSs | 100 | SiO2 | T1-/T2-weighted MRI | [83] |
| MnSiO3@Fe3O4 | 198 | SiO2 | T1-/T2-weighted MRI | [84] |
| FeCUPs | 216 | – | T2-weighted MRI/FLI | [86] |
| Ag-HPB | 69 | Acid etching | T1-weighted MRI/PAI | [89] |
| Fe3O4@ZrO2 | 155 | SiO2 | T2-weighted MRI/CT imaging | [90] |
| MM@HMFe@BS | 148 | SiO2 | T2-weighted MRI and CDT/metastasis inhibition | [99] |
| MFe3O4-Cy5.5 | 190 | – | T2-weighted MRI/PAI/FLI and Surgery/PTT | [100] |
| DOX-HMNCs | 215 ± 20 | Ostwald ripening | T2-weighted MRI and PTT/CDT/chemotherapy | [106] |
| MHPCNs-SS-PGA-FA/DOX | 127 | SiO2 | T2-weighted MRI and PTT/chemotherapy | [59] |
| Fe3O4@PDA@Pt-PEG-Ce6 | 160 | PS | T2-weighted MRI/FLI/USI and PDT/PTT | [107] |
| O2@PFC@MF-2@PEG/Dox | 150 | Self-assembly | T2-weighted MRI/CT imaging and chemotherapy/PDT/PTT | [108] |
| Fe-Ga/BSA@DOX | 200 | – | T1-/T2-weighted MRI and chemotherapy/PTT/CDT | [110] |
| hM@ZMDF | 102 ± 13 | spindle-like MIL-88B(Fe) NPs | T2-weighted MRI/FLI and chemotherapy/CDT | [113] |
| DOX@Fe-HMON-Tf | 71 | SiO2 | T2-weighted MRI and ferroptosis/chemotherapy | [118] |
| HMPB-Mn-DOX | 290 | Acid etching | T1-weighted MRI and PTT/chemotherapy | [122] |
| HMNP-PB@Pent@DOX | 131.5 | PS | T2-weighted MRI/PAI and chemotherapy/PTT | [125] |