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Survival of G. mellonella larvae following administration of PLGA-NPs, PTB, and PLGA-PTB-NPs by intra-hemocoel injection. Every experiment was conducted with 10 larvae for each group in triplicate. All values are the mean of three independent experiments.
| Chemical | LD50 (mg/kg) | Solvent |
|---|---|---|
| PLGA-NPs | >2.85 | H2O |
|
PTB PLGA-PTB-NPs |
>1.35 >2.85–1.35 |
100 H2O:1 DMSO 100 H2O:1 DMSO |
