Table 3.
Comparing of difference in level of parameters between the intervention and control groups at the end of follow up.
| Standard treatment plus NBS powder (n = 24) | Standard treatment (n = 23) | ||
|---|---|---|---|
| Normally distributed parameters | Difference | Difference | P** |
| WBC (×109/L) | 1.83 (1.28) | 0.78 (0.69) | 0.001 |
| RBC (×106/µL) | 0.13 (0.57) | 0.34 (0.69) | 0.26 |
| Hb (g/dl) | -0.11 (0.39) | -0.12 (0.44) | 0.94 |
| MCV (fL) | -0.02 (4.50) | 1.53 (4.21) | 0.23 |
| MCH (pg) | 0.62 (1.84) | 0.79 (1.94) | 0.77 |
| ESR (mm/hr) | -23.71 (16.83) | -21.08 (13.99) | 0.56 |
| SGPT (IU/L) | -6.33 (11.51) | 1 (3.63) | 0.005 |
| LDH (U/L) | -273 (175.29) | -221.26 (118.20) | 0.24 |
| NEU (×103/mm3) | -6.08 (9.09) | -0.87 (8.67) | 0.05 |
| LYM (×103/mm3) | 9.29 (8.60) | 4.17 (8.65) | 0.05 |
| IL-2 (pg/mL) | -3.84 (1.91) | -2.91 (0.92) | 0.04 |
| IL-6 (pg/mL) | -36.19 (15.37) | -25.91 (11.51) | 0.01 |
| IL-17 (pg/mL) | -28.96 (12.22) | -22.70 (12.19) | 0.08 |
| TNF-α (pg/mL) | -36.80 (12.35) | -28.69 (6.97) | 0.008 |
| IFN-γ (pg/mL) | -18.64 (3.65) | -18.12 (4.15) | 0.67 |
| Non-normally distributed parameters | Difference | Difference | P§ |
| PLT (×103/mm3) | 64 (94.5) | 57 (98) | 0.28 |
| SAA (U/mL) | -10 (31.5) | -9 (15) | 0.61 |
| hs-CRP (mg/L) | -16.5 (11.5) | -18 (24) | 0.76 |
| SGOT (IU/L) | -2.5 (7) | 1 (3) | 0.005 |
| ALP (IU/L) | -112 (141) | -83 (93) | 0.04 |
| CPK (U/L) | -58.5 (104.5) | -23 (48) | 0.03 |
| MON (×103/mm3) | -2 (2) | -2 (2) | 0.32 |
| EOS (×103/mm3) | 0 (2) | -1 (2) | 0.42 |
WBC, White Blood Cell; RBC, Red Blood Cell; HB, Hemoglobin; MCV, Mean Corpuscular Volume; MCH, Mean Corpuscular Hemoglobin; ESR, Erythrocyte Sedimentation Rate; SGPT, Serum Glutamate-Pyruvate Transaminase; van der Wal et al., Lactate Dehydrogenase; Neuman et al., Neutrophil; LYM, Lymphocyte; IL-2, Interleukin-2; IL-6, Interleukin 6; IL-17, Interleukin 17; TNF-alpha, Tumor Necrosis Factor; Nori et al., Interferon; PLT, Platelet; Kasliwal et al., Serum Amyloid A; hs-CRP, High-Sensitivity C-reactive Protein; SGOT, Serum Glutamic-Oxaloacetic Transaminase; ALP, Alkaline Phosphatase; CPK, Creatine Phosphokinase; MON, Monocytes; EOS, Eosinophil.
Normally and non-normally distributed parameters were presented as mean (SD) and median (IQR), respectively.
** Independent t-test, § Mann-Whitney test. Bold values: P value ≥ 0.05.