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. 2022 Sep 7;154(10):e202213084. doi: 10.1085/jgp.202213084

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© 2022 Nourse et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure S8. — Cholesterol supplementation does not rescue Piezo1 KO NSC oligodendrocyte differentiation. Gardner-Altman estimation plot of O4+ oligodendrocytes formed in Piezo1 KO mNSCs with and without cholesterol-MBCD treatment. Data are normalized to untreated WT samples. n = 6 samples from 5 embryos, 25,704 cells quantified from 80 unique fields of view for WT, and n = 6 samples from 4 embryos, 30,301 cells quantified from 76 unique fields of view for Piezo1 KO and 33,355 cells quantified from 60 unique fields of view for Piezo1 KO + cholesterol from two independent experiments (Cohen’s d = −0.587). Related to Fig. 5.