TABLE 4.
Relapse, breast cancer disease‐specific survival and overall survival according to treatment combination
| Treatment combination | Total n (%) | Recurrence | BC DSS | OS | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Yes n (%) | No n (%) | p | Alive n (%) | Dead n (%) | p | Alive n (%) | Dead n (%) | p | ||
| NACT + S + RT + ACT | 0.339 | 0.160 | 0.128 | |||||||
| Yes | 33 (15.7) | 17 (18 .9) | 16 (13.3) | 18 (12.9) | 15 (21.1) | 14 (12.1) | 19 (20.2) | |||
| No | 177 (84.3) | 73 (81.1) | 104 (86.7) | 121 (87.1) | 56 (78.9) | 102 (87.9) | 75 (79.8) | |||
| NACT + S + RT | 0.017 | 0.037 | 0.006 | |||||||
| Yes | 37 (17.6) | 9 (10.0) | 28 (23.3) | 30 (21.6) | 7 (9.9) | 28 (24.1) | 9 (9.6) | |||
| No | 173 (82.4) | 81 (90.0) | 92 (76.7) | 109 (78.4) | 64 (90.1) | 88 (75.9) | 85 (90.4) | |||
| S + RT + ACT | 0.150 | 0.004 | 0.098 | |||||||
| Yes | 19 (9.0) | 5 (5.6) | 14 (11.7) | 18 (12.9) | 1 (1.4) | 14 (12.1) | 5 (5.3) | |||
| No | 191 (91.0) | 85 (94.4) | 106 (88.3) | 121 (87.1) | 70 (98.6) | 102 (87.9) | 89 (94.7) | |||
| NACT + S + ACT | 0.147 | 0.090 | 0.037 | |||||||
| Yes | 52 (24.8) | 27 (30.0) | 25 (20.8) | 29 (20.9) | 23 (32.4) | 22 (19.0) | 30 (31.9) | |||
| No | 158 (75.2) | 63 (70.0) | 95 (79.2) | 110 (79.1) | 48 (67.6) | 94 (81.0) | 64 (68.1) | |||
| NACT + S | 0.405 | 0.514 | 0.836 | |||||||
| Yes | 27 (12.9) | 14 (15.6)) | 13 (10.8) | 16 (11.5) | 11 (15.5) | 14 (12.1) | 13 (13.8) | |||
| No | 183 (87.1) | 76 (84.4) | 107 (89.2) | 123 (88.5) | 60 (84.5) | 102 (87.9) | 81 (86.2) | |||
| S + ACT | 0.678 | 1.000 | 0.836 | |||||||
| Yes | 27 (12.9) | 13 (14.4) | 14 (11.7) | 18 (12.9) | 9 (12.7) | 14 (12.1) | 13 (13.8) | |||
| No | 158 (75.2) | 77 (85.6) | 106 (88.3) | 121 (87.1) | 62 (87.3) | 102 (87.9) | 81 (86.2) | |||
| S + RT | 1.000 | 1.000 | 1.000 | |||||||
| Yes | 1 (0.5) | 0 (0.0) | 1 (0.8) | 1 (0.9) | 0 (0.0) | 1 (0.7) | 0 (0.0) | |||
| No | 209 (99.5) | 90 (100) | 119 (99.2) | 115 (99.1) | 94 (100) | 138 (99.3) | 94 (100) | |||
| Surgery alone | 0.781 | 1.000 | 0.584 | |||||||
| Yes | 14 (6.7) | 5 (5.6) | 9 (7.5) | 9 (6.5)) | 5 (7.0) | 9 (7.8) | 5 (5.3) | |||
| No | 196 (93.3) | 85 (94.4) | 111 (92.5) | 130 (93.5) | 66 (93.0) | 107 (92.2) | 89 (94.7) | |||
| Total | 210 (100) | 90 (42.9) | 120 (57.1) | 139 (66.2) | 71 (33.8) | 116 (55.2) | 94 (44.8) | |||
Abbreviations: ACT, adjuvant chemotherapy; BC DSS, breast cancer disease specific survival; NA, not applicable; NACT, neoadjuvant chemotherapy; OS, overall survival; p, p value; RT, radiotherapy; S, surgery.