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. 2022 May 16;5(9):e1624. doi: 10.1002/cnr2.1624

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© 2022 The Authors. Cancer Reports published by Wiley Periodicals LLC.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Histological findings of Case 1. (A) Focal necrosis is present in the lobular parenchyma (hematoxylin and eosin staining, ×20). (B) A damaged interlobular bile duct has an irregular configuration and intraepithelial inflammatory cells. The surrounding infiltrate is rich in lymphocytes (hematoxylin and eosin staining, ×40). (C) CD8‐positive cells are present in the portal area and the lobular parenchyma (CD8 staining, ×20). (D) Distribution of CD3‐positive cells similar to that of CD8‐positive cells (CD3 staining, ×20)