Table 2.
Multivariable linear regression models evaluating the relationship of baseline urine uromodulin levels, indexed to creatinine, with 24-hour mean systolic and diastolic blood pressure.
Predictor | Outcome: 24-hour Systolic Mean BP |
Outcome: 24-hour Diastolic Mean BP |
||
---|---|---|---|---|
Estimate (95% CI) | p-value | Estimate (95% CI) | p-value | |
Umod/Cr, per doubling | −0.30 (−1.08, 0.48) | 0.45 | −0.06 (−0.66, 0.55) | 0.86 |
Age, per year | 1.08 (0.76, 1.39) | <0.0001 | 0.20 (−0.05, 0.44) | 0.12 |
Male sex | 3.40 (1.21, 5.59) | 0.002 | 0.03 (−1.68, 1.74) | 0.97 |
BMI z-score | 0.74 (−0.24, 1.72) | 0.14 | −0.92 (−1.69, −0.15) | 0.02 |
Black racea | 3.86 (0.99, 6.73) | 0.008 | 2.54 (0.30, 4.78) | 0.03 |
Hispanic ethnicityb | −1.10 (−4.24, 2.04) | 0.49 | −0.67 (−3.13, 1.78) | 0.59 |
Glomerular diagnosis | −0.68 (−3.42, 2.06) | 0.63 | 1.31 (−0.83, 3.45) | 0.23 |
Birth weight, per kg | −0.16 (−1.72, 1.39) | 0.84 | 0.78 (−0.43, 2.00) | 0.21 |
eGFR, per 10% decrease | 0.06 (−0.22, 0.33) | 0.69 | 0.11 (−0.11, 0.32) | 0.32 |
Antihypertensive use | −0.47 (−2.84, 1.91) | 0.70 | −1.81 (−3.67, 0.05) | 0.06 |
Sodium intake, per g/day | −0.04 (−0.41, 0.32) | 0.81 | −0.15 (−0.43, 0.14) | 0.31 |
Abbreviations: BP, blood pressure; BMI, body mass index; eGFR, estimated glomerular filtration rate.
Reference group for race is non-Black: including White, Asian, Pacific Islander.
Reference group for ethnicity is non-Hispanic.