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. Author manuscript; available in PMC: 2023 Oct 1.
Published in final edited form as: Hypertension. 2022 Aug 3;79(10):2298–2304. doi: 10.1161/HYPERTENSIONAHA.122.19566

Table 2.

Multivariable linear regression models evaluating the relationship of baseline urine uromodulin levels, indexed to creatinine, with 24-hour mean systolic and diastolic blood pressure.

Predictor Outcome: 24-hour
Systolic Mean BP
Outcome: 24-hour
Diastolic Mean BP
Estimate (95% CI) p-value Estimate (95% CI) p-value
Umod/Cr, per doubling −0.30 (−1.08, 0.48) 0.45 −0.06 (−0.66, 0.55) 0.86
Age, per year 1.08 (0.76, 1.39) <0.0001 0.20 (−0.05, 0.44) 0.12
Male sex 3.40 (1.21, 5.59) 0.002 0.03 (−1.68, 1.74) 0.97
BMI z-score 0.74 (−0.24, 1.72) 0.14 −0.92 (−1.69, −0.15) 0.02
Black racea 3.86 (0.99, 6.73) 0.008 2.54 (0.30, 4.78) 0.03
Hispanic ethnicityb −1.10 (−4.24, 2.04) 0.49 −0.67 (−3.13, 1.78) 0.59
Glomerular diagnosis −0.68 (−3.42, 2.06) 0.63 1.31 (−0.83, 3.45) 0.23
Birth weight, per kg −0.16 (−1.72, 1.39) 0.84 0.78 (−0.43, 2.00) 0.21
eGFR, per 10% decrease 0.06 (−0.22, 0.33) 0.69 0.11 (−0.11, 0.32) 0.32
Antihypertensive use −0.47 (−2.84, 1.91) 0.70 −1.81 (−3.67, 0.05) 0.06
Sodium intake, per g/day −0.04 (−0.41, 0.32) 0.81 −0.15 (−0.43, 0.14) 0.31

Abbreviations: BP, blood pressure; BMI, body mass index; eGFR, estimated glomerular filtration rate.

a

Reference group for race is non-Black: including White, Asian, Pacific Islander.

b

Reference group for ethnicity is non-Hispanic.