Table 4.
Age stratified hazard ratio for mood disorders in patients with AMD compared with individuals without AMD.
| Event | Incidence rate# (95% CI) | aHR (95% CI) | |
|---|---|---|---|
| Non-AMD | AMD | ||
| Any psychological care | P for interaction = 0.002 | ||
| Age 50–70 years | 7.36 (6.55–8.28) | 11.38 (9.99–12.95) | 1.51 (1.26–1.80)* |
| Age 71–100 years | 13.53 (12.12–15.11) | 14.45 (12.53–16.65) | 1.01 (0.84–1.21) |
| Behavioral therapy | P for interaction = 0.020 | ||
| Age 50–70 years | 4.70 (4.06–5.44) | 7.72 (6.60–9.02) | 1.60 (1.29–1.98)* |
| Age 71–100 years | 8.26 (7.18–9.51) | 9.67 (8.14–11.49) | 1.11 (0.89–1.39) |
| Sleep or anxiety-related disorders | P for interaction = 0.346 | ||
| Age 50–70 years | 3.55 (3.00–4.20) | 5.71 (4.77–6.85) | 1.59 (1.24–2.03)* |
| Age 71–100 years | 4.73 (3.93–5.69) | 6.25 (5.05–7.74) | 1.29 (0.97–1.72) |
| MDD | P for interaction = 0.205 | ||
| Age 50–70 years | 1.80 (1.42–2.28) | 2.98 (2.33–3.83) | 1.60 (1.13–2.25)* |
| Age 71–100 years | 3.07 (2.45–3.86) | 3.68 (2.79–4.85) | 1.16 (0.81–1.66) |
AMD age-related macular degeneration, aHR adjusted hazard ratio adjusted for age, sex, education, marital status, and comorbidities, CI confidential interval, MDD major depression disorder.
*Significant result for null hypothesis of aHR = 1.
#Crude incidence rate per 10,000 person-months.