Table 5.
Sex stratified hazard ratio for mood disorders in patients with AMD compared with individuals without AMD.
| Event | Incidence rate# (95% CI) | aHR (95% CI) | |
|---|---|---|---|
| Non-AMD | AMD | ||
| Any psychological care | P for interaction = 0.008 | ||
| Male | 10.16 (9.15–11.28) | 11.45 (10.03–13.07) | 1.09 (0.92–1.29) |
| Female | 9.11 (8.03–10.33) | 14.15 (12.32–16.26) | 1.54 (1.27–1.86)* |
| Behavioral therapy | P for interaction = 0.027 | ||
| Male | 6.50 (5.71–7.40) | 7.95 (6.79–9.31) | 1.18 (0.96–1.45) |
| Female | 5.48 (4.66–6.44) | 9.23 (7.78–10.95) | 1.68 (1.33–2.13)* |
| Sleep or anxiety-related disorders | P for interaction = 0.802 | ||
| Male | 3.62 (3.04–4.30) | 5.50 (4.55–6.64) | 1.50 (1.16–1.94)* |
| Female | 4.50 (3.77–5.38) | 6.50 (5.31–7.96) | 1.43 (1.09–1.87)* |
| MDD | P for interaction = 0.400 | ||
| Male | 2.19 (1.75–2.73) | 2.88 (2.22–3.74) | 1.27 (0.90–1.78) |
| Female | 2.41 (1.90–3.07) | 3.76 (2.89–4.90) | 1.57 (1.10–2.25)* |
AMD age-related macular degeneration, aHR adjusted hazard ratio which adjusted for age, sex, education, marital status, and comorbidities, CI confidential interval, MDD major depression disorder.
*Significant result for null hypothesis of aHR = 1.
#Crude incidence rate per 10,000 person-months.