Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 8;8:103. doi: 10.1038/s41523-022-00473-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — Correlation between chronological age and expression levels of p16 mRNA (log2) (a), calculated p16Age (b) and p16Age Gap (d) and 16Age and p16Age gap (e). Distribution of p16, p16Age, p16Age Gap and chronological age are summarized in a histogram (c). The histogram shows a bar for grouped values of each continuous variable. The outlier box plot in each graph shows quantiles of continuous distributions. The horizontal line within the box represents the median sample value. The confidence diamond contains the mean and the upper and lower 95% of the mean. p16Age (and therefore log2 p16) is highly correlated with p16Age Gap.