Table 2.

Univariable analysis for overall survival

	HR	95% CI	p value
Age*	0.998	0.962–1.036	0.915
Gender (female)	0.916	0.675–1.243	0.571
Treatment primary tumor
Enucleation	–	–	–
Radiotherapy	0.933	0.763–1.140	0.497
Vascularity liver metastases
Hypervascular	–	–	–
Hypovascular	0.852	0.434–1.673	0.642
Mixed	1.064	0.540–2.094	0.858
Previous treatment liver metastases
None	–	–	–
Systemic	1.180	0.520–2.680	0.693
Local	1.470	0.944–2.287	0.088
Combination	0.496	0.161–1.533	0.223
Number liver metastases
< 5	–	–	–
6–9	1.135	0.527–2.444	0.747
> 9	1.526	0.855–2.723	0.153
Sum target lesions*	1.037	1.008–1.067	0.013
Number M-PHP procedures > 1	0.450	0.224–0.905	0.025
Interval primary to liver (months)*	0.996	0.987–1.005	0.404
LDH at baseline
Normal**	–	–	–
< 2× ULN	1.424	1.245–1.630	< 0.001
> 2× ULN	3.687	1.370–9.922	0.010

*Continuous variable

**Normal LDH value: < 248 U/L