Table 5.
Diameters of zones of bacterial inhibition obtained using AzA, TTO, AzA, and TTO, ME and ME hydrogel composite formulations
| Formulations | Concentration | Vol. used | Diameter obtained for the zone of inhibition, σ ± SD (mm) (amount of antibacterial tested (mg/mL)) | ||
|---|---|---|---|---|---|
| ATCC 29,213 (S. aureus) | MTCC 3382 (S. epidermidis) | MTCC1951 (P. acnes) | |||
| AzA | 50 mg/mL | 80 μL | 21.3 ± 0.5 | 20.6 ± 1.1 | 11.3 ± 0.5 |
| EO | 50 mg/mL | 80 μL | ND | ND | 12.3 ± 0.5 |
| AzA with EO | 50 + 50 mg/mL | 80 μL | 15.3 ± 1.5 | 16 ± 1.0 | ND |
| ME | 50 mg/mL | 80 μL | 23 ± 1.0 | 23.6 ± 1.5 | 22.3 ± 0.5 |
| Hydrogel Composite | 50 mg/mL | 80 μL | 19 ± 1.7 | 19.3 ± 0.5 | 18.3 ± 0.5 |
| Erythromycin (+ ve) | 1 mg/mL | 10 μL | 23 ± 1.0 | 29 ± 1.0 | 12 ± 0 |
| Ethanol (−ve) | - | 80 μL | ND | ND | ND |
| DMSO (−ve) | - | 80 μL | ND | ND | ND |
ND no zone of inhibition detected; the zone of inhibition values are an average from two independent experiments, EO tea tree oil, AzA azelaic acid