Fig. 9. Effects of DHA injection and colistin combination therapy against E. coli W3110 (pUC19-mcr-1) in vivo.
a Mouse infection model monitoring including survival rate, time of treatment, Wt. Loss (weight loss), morbidity score, bacterial loading and histopathological observation. b Survival plot of mice inoculated via intraperitoneal injection with E. coli W3110 (pUC19-mcr-1) (17 mice per group). c–h The Wt. Loss (c), morbidity score (d), histopathological observation (e) and the bacterial burden in the blood (f), liver (g) and spleen (h) were calculated (n = 10). **P < 0.01. ns indicates no significant.