Table 4.
Univariate and multivariate Cox hazards analyses for predicting 4 year MACEs.
| Variable | Unadjusted HR | 95% CI | P-value | Adjusted HR | 95% CI | P-value |
|---|---|---|---|---|---|---|
| Male sex | 2.0606 | 0.7092–5.9871 | 0.1840 | |||
| BMI | 1.0813 | 0.9826–1.1900 | 0.1095 | |||
| Smoking | 0.5491 | 0.2205–1.3674 | 0.1978 | |||
| Statin | 1.9332 | 0.8871–4.2128 | 0.0972 | |||
| eGFR | 0.9999 | 0.9472–1.0263 | 0.9958 | |||
| HDL-C | 1.0190 | 0.9906–1.0481 | 0.1914 | |||
| LDL-C | 0.9889 | 0.9760–1.0020 | 0.0974 | |||
| Apo-A1 | 1.0081 | 0.9889–1.0277 | 0.4114 | |||
| Apo-B | 1.0111 | 0.9960–1.0262 | 0.1509 | |||
| Apo-C3 | 1.0758 | 0.9691–1.1943 | 0.1704 | |||
| %FI | 0.9581 | 0.9028–1.0166 | 0.1571 | |||
| %FF | 0.9509 | 0.8962–1.0089 | 0.0955 | |||
| %NC | 1.1207 | 1.0337–1.2151 | 0.0057* | 1.0960 | 1.0099–1.1894 | 0.0280* |
| %DC | 1.1454 | 1.0482–1.2581 | 0.0046* | |||
| High apo-C3 | 3.4977 | 1.4696–8.3258 | 0.0047* | 2.9381 | 1.2106–7.0820 | 0.0171* |
apo-C3 Apolipoprotein C3; MACE Major cardiovascular event; HR Hazard ratio; CI Confidence interval; BMI Body mass index; eGFR, Estimated glomerular filtration rate; HDL-C High-density lipoprotein cholesterol;LDL-C Low-density lipoprotein cholesterol; %FI Percentage of the FI volume in the plaque volume; %FF Percentage of the FF volume in the plaque volume; %NC Percentage of the NC volume in the plaque volume; %DC Percentage of the DC volume in the plaque volume; high apo-C3, patients with apo-C3 > 8.5 mg/dL. * P < 0.05.