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. 2022 Aug 26;9:974902. doi: 10.3389/fnut.2022.974902

TABLE 2.

Potential biomarkers discovered by VIP, FC, and adjusted p-values.

Different metabolites VIP FC P-value
NC vs. GDM
C18:1 2.45 1.24 0.003
2-Hydroxybutyric acid 1.91 1.62 0.001
Pyroglutamic acid 2.89 0.65 <0.001
Glutamic acid 1.27 1.21 0.042
NC vs. HP
C16:0 2.67 1.32 <0.001
C18:0 1.27 1.24 0.011
C18:1 2.18 1.47 <0.001
Pyroglutamic acid 1.82 1.44 0.001
Glycine 1.20 1.25 0.008
γ-Aminobutyric acid 5.57 1.36 <0.001
Glutamic acid 1.33 1.33 0.001
GDM vs. HP
C18:1 1.11 1.21 0.005
Pyroglutamic acid 2.84 2.21 <0.001
γ-Aminobutyric acid 5.84 1.38 <0.001
Creatinine 1.03 1.48 <0.001

P-values in bold indicate that there are significant differences between the NC, GDM, and HP groups.