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. 2022 Aug 26;12:941496. doi: 10.3389/fonc.2022.941496

Table 1.

Demographics and clinical characteristics of the sample (N = 317).

Characteristic Category Mean ± SD (range) or n (%)
Age (years) 52.78 ± 10.41 (26–82)
20–29 3 (0.95)
30–39 31 (9.78)
40–49 93 (29.34)
50–59 107 (33.75)
≥60 83 (26.18)
Stage of tumor I 6 (1.96)
II 224 (73.20)
III 76 (24.84)
Initial clinical T stage 1 30 (9.86)
2 212 (69.74)
3 32 (10.53)
4 29 (9.54)
Initial clinical N stage 0 114 (37.50)
1 148 (48.68)
2 19 (6.25)
3 23 (7.57)
Ki-67 Low (<14%) 34 (11.26)
High (≥14%) 268 (88.75)
Tumor subtype HR+/HER2− 108 (34.07)
HR+/HER2+ 49 (15.46)
HR−/HER2+ 58 (18.30)
TNBC 102 (32.18)
Chemotherapy regimen AC-T regimen 214 (67.51)
TCHP regimen 84 (26.50)
Other 19 (5.99)
Duration of neoadjuvant chemotherapy (days) 142 ± 30.86 (49–196)
BMI at baseline <18.5 (underweight) 9 (2.84)
18.5–22.9 (normal) 132 (41.64)
23–24.9 (overweight) 82 (25.87)
≥25 (obese) 94 (29.65)

AC-T regimen, combination of an anthracycline and cyclophosphamide, followed by a taxane; BMI, body mass index; HER2−, human epidermal growth factor receptor 2-negative; HER2+, human epidermal growth factor receptor 2-positive; HR−, hormone receptor-negative; HR+, hormone receptor-positive; TCHP regimen, docetaxel, carboplatin, trastuzumab, and pertuzumab; TNBC, triple negative breast cancer.