TABLE 2.
Chi-square analysis of differences in influencing factors among different subtypes (n = 17,695).
| IBS-C n = 2,608 | IBS-D n = 4,448 | IBS-M n = 10,436 | IBS-U n = 203 | p-value | |
|---|---|---|---|---|---|
| Sex | <0.001 | ||||
| Female | 2,246 (86.1%) | 3,239 (72.8%) | 7,912 (75.8%) | 147 (72.4%) | |
| Male | 362 (13.9%) | 1,209 (27.2%) | 2,524 (24.2%) | 56 (27.6%) | |
| Age (years) | <0.001 | ||||
| Mean (SD) | 54.41 (7.858) | 54.26 (7.766) | 54.35 (7.788) | 57.22 (7.483) | |
| Median (IQR) | 55 (48, 61) | 54 (48, 61) | 55 (48, 61) | 58 (52, 63) | |
| Townsend Deprivation Score | 0.009 | ||||
| Mean (SD) | −1.57 (2.902) | −1.47 (2.944) | −1.35 (3.063) | −1.81 (2.704) | |
| Median (IQR) | −2.33 (−3.76, 0.01) | −2.26 (−3.71, 0.30) | −2.18 (−3.67, 0.50) | −2.45 (−3.85, −0.53) | |
| Missing data | 4 (0.2%) | 7 (0.2%) | 17 (0.2%) | 2 (1.0%) | |
| Ever been offered/sought treatment for anxiety | 0.003 | ||||
| Yes | 931 (35.7%) | 1,628 (36.6%) | 4,059 (38.9%) | 74 (36.5%) | |
| No | 1,667 (63.9%) | 2,813 (63.2%) | 6,326 (60.6%) | 129 (63.5%) | |
| Missing data | 10 (0.4%) | 7 (0.2%) | 51 (0.5%) | 0 (0.0%) | |
| Ever been offered/sought treatment for depression | <0.001 | ||||
| Yes | 1,026 (39.3%) | 1713 (38.5%) | 4,421 (42.4%) | 68 (33.5%) | |
| No | 1,568 (60.1%) | 2,721 (61.2%) | 5,969 (57.2%) | 133 (65.5%) | |
| Missing data | 14 (0.5%) | 14 (0.3%) | 46 (0.4%) | 2 (1.0%) | |
| Family history of IBS | <0.001 | ||||
| Yes | 686 (26.3%) | 1,223 (27.5%) | 3,048 (29.2%) | 36 (17.7%) | |
| No | 1,269 (48.7%) | 2082 (46.8%) | 4,397 (42.1%) | 111 (54.7%) | |
| Missing data | 653 (25.0%) | 1,143 (25.7%) | 2,991 (28.7%) | 56 (27.6%) | |
| Long-term/recurrent antibiotics as child or teenager | <0.001 | ||||
| Yes | 587 (22.5%) | 968 (21.8%) | 2,562 (24.5%) | 46 (22.7%) | |
| No | 1,652 (63.3%) | 2,902 (65.2%) | 6,316 (60.5%) | 133 (65.5%) | |
| Missing data | 369 (14.1%) | 578 (13.0%) | 1,558 (14.9%) | 24 (11.8%) | |
| Diagnosed with coeliac disease or gluten sensitivity | 0.959 | ||||
| Yes | 133 (5.1%) | 222 (5.0%) | 523 (5.0%) | 12 (5.9%) | |
| No | 2,408 (92.3%) | 4,123 (92.7%) | 9,630 (92.3%) | 190 (93.6%) | |
| Missing data | 67 (2.6%) | 103 (2.3%) | 283 (2.7%) | 1 (0.5%) | |
| PHQ-12 Score | <0.001 | ||||
| ≤6 | 928 (35.6%) | 1,725 (38.8%) | 3,012 (28.9%) | 83 (40.9%) | |
| >6 | 1,573 (60.3%) | 2,555 (57.4%) | 6,933 (66.4%) | 113 (55.7%) | |
| Missing data | 107 (4.1%) | 168 (3.8%) | 491 (4.7%) | 7 (3.4%) | |
Data were mean (SD) or n (%) unless noted otherwise. The distribution of age and the Townsend Deprivation Score is non-normal; therefore, the mean (SD) and median (P25 and P75) are used to describe. The p-value was calculated by the chi-square test and Wilcoxon’s rank-sum test where applicable. In this analysis, “Do not know,” “Prefer not to answer,” and “missing” were coded as missing data.