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. 2022 Aug 26;10:961898. doi: 10.3389/fbioe.2022.961898

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Copyright © 2022 Wang, Xiao, Zhong, Zhang, Yin, Gao and Song.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Histological and histomorphometric analyses. (A) Schematic illustration of histomorphometric measurements. N: notch; V: vertex of furcation; NC: new cementum; NC% = NC/NV×100%; NP: new periodontal ligament; NP% = NP/NV×100%; NBA: new bone area; DA: defect area; NBA% = NBA/DA×100%. (B) Representative H&E staining of the furcation area. The dotted lines indicate a new bone formation area. Scale bar, 400 μm. (C) Quantitative analysis of new cementum formation, periodontal ligament formation, and bone formation areas. Data are presented as mean ± SD, *p < 0.05.